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spironolactone


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(spy-rŏ-noh-lak-tohn)

a synthetic corticosteroid that inhibits the activity of the hormone aldosterone and is administered by mouth as a potassium-sparing diuretic to treat fluid retention (oedema) in cirrhosis, ascites, and severe heart failure. It is also used in treating aldosteronism. Trade name: Aldactone.

Subjects: Clinical Pharmacology and Therapeutics.


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