1. Src-like adaptor proteins. Dimeric adaptor proteins, SLA (281 aa) and SLA2 (261 aa), that are negative regulators of T-cell and B-cell immune responses. Through their SH3 and SH2 domains they interact with the T- or B-cell receptor complexes and with the ubiquitin ligase, cbl.
2. Sarcolemmal-associated protein, an integral membrane protein (828 aa with smaller isoforms) that may interact with myosin and is found in transverse tubules, near the junctional sarcoplasmic reticulum and along the Z- and M-lines in cardiomyocytes. NB The term ‘sarcolemmal associated protein’ is also used loosely of dystrophin
Users without a subscription are not able to see the full content. Please,
or login to access all content.