streptococcal pyrogenic exotoxins

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'streptococcal pyrogenic exotoxins' can also refer to...

streptococcal pyrogenic exotoxins

Presence of streptococcal pyrogenic exotoxin A and C genes in human isolates of group G streptococci

The superantigenic activity of streptococcal pyrogenic exotoxin B is independent of the protease activity

Streptococcal Pyrogenic Exotoxin B Cleaves Human S-Adenosylhomocysteine Hydrolase and Induces Hypermethioninemia

Streptococcal Pyrogenic Exotoxin B Enhances Tissue Damage Initiated by Other Streptococcus pyogenes Products

Acute poststreptococcal glomerulonephritis with acute interstitial nephritis related to streptococcal pyrogenic exotoxin B

Invasive Group A Streptococcal Disease in Taiwan Is Not Associated with the Presence of Streptococcal Pyrogenic Exotoxin Genes

Potentiation of lethal endotoxin shock by streptococcal pyrogenic exotoxin in rabbits: Possible relevance of hyperreactivity of macrophages to endotoxin

Dissemination of streptococcal pyrogenic exotoxin G (spegg) with an IS-like element in fish isolates of Streptococcus dysgalactiae

Streptococcal Pyrogenic Exotoxin A Release, Distribution, and Role in a Murine Model of Fasciitis and Multiorgan Failure Due to Streptococcus pyogenes

Th1-type cytokine mRNA in rheumatoid arthritis mononuclear cells induced by streptococcal pyrogenic exotoxin A

Superantigen-like gene(s) in human pathogenic Streptococcus dysgalactiae, subsp. equisimilis: genomic localisation of the gene encoding streptococcal pyrogenic exotoxin G (speGdys )

Lethal Shock Induced by Streptococcal Pyrogenic Exotoxin A in Mice Transgenic for Human Leukocyte Antigen–DQ8 and Human CD4 Receptors: Implications for Development of Vaccines and Therapeutics

Invasive Group A Streptococcal Infections: T1M1 Isolates Expressing Pyrogenic Exotoxins A and B in Combination with Selective Lack of Toxin-Neutralizing Antibodies Are Associated with Increased Risk of Streptococcal Toxic Shock Syndrome


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(SPE, formerly

A group of toxins produced by Streptococcus pyogenes and responsible for many of the pathological sequelae of infection. Several (SPEA, SPEC, SPEX) are superantigens. SPEB is a cysteine peptidase (streptopain: peptidase, 398 aa) which possesses mitogenic activity but, when pure, is not a superantigen. SPEA (streptococcal pyrogenic exotoxin A) is a phage-encoded exotoxin. SPEA and SPEC show strong sequence homology to the staphylococcal enterotoxins.

Subjects: Medicine and Health.

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