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'survivin' can also refer to...



Survivin and aven: two distinct antiapoptotic signals in acute leukemias

Activation of Cancer-Specific Gene Expression by the Survivin Promoter

Experimental cancer gene therapy by multiple anti-survivin hammerhead ribozymes

Targeting survivin in cancer therapy: fulfilled promises and open questions

MYCN and survivin cooperatively contribute to malignant transformation of fibroblasts

Transcriptional expression of survivin and its splice variants in endometriosis

Expression of survivin and Bcl-2 in the normal human endometrium

Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance

Increased Survivin mRNA in Malignant Pleural Effusion is Significantly Correlated with Survival

Expression of the Antiapoptosis Gene Survivin Predicts Poor Prognosis of Stage III Gastric Adenocarcinoma

The Prognostic Value of Survivin Expression in Patients with Colorectal Carcinoma: A Meta-analysis

Effects of Survivin Antagonists on Growth of Established Tumors and B7-1 Immunogene Therapy

Quercetin promotes degradation of survivin and thereby enhances death-receptor–mediated apoptosis in glioma cells

A study into the potential role of Survivin localization in resistance to drug-induced apoptosis

Survivin expression in oesophageal squamous cell carcinoma: its prognostic impact and splice variant expression

Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy

Survivin repression by p53, Rb and E2F2 in normal human melanocytes


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An inhibitor of apoptosis (baculoviral IAP repeat-containing protein, BIRC-5, 142 aa) that is selectively overexpressed in common human cancers. It is expressed in the G2/M phase of the cell cycle and associates with spindle microtubules; disruption of the survivin-microtubule interaction results in increased activity of caspase-3 and apoptotic death. Several splice variants have been described. Interacts with XIAP.

Subjects: Chemistry — Medicine and Health.

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