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syk


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Syk

syk

Linking inflammation and cancer: the unexpected SYK world

Protein Tyrosine Kinase, Syk: A Key Player in Phagocytic Cells

Structure and Function of Syk Protein-Tyrosine Kinase

3849Involvement of B cell/Syk axis in development of abdominal aortic aneurysm

SYK inhibition blocks proliferation and migration of glioma cells and modifies the tumor microenvironment

Purification of a 72-kDa Protein-Tyrosine Kinase from Rat Liver and Its Identification as Syk: Involvement of Syk in Signaling Events of Hepatocytes

Syk contributes to PDGF-BB-mediated migration of rat aortic smooth muscle cells via MAPK pathways

Degradation of 3-O-methylgallate in Sphingomonas paucimobilis SYK-6 by pathways involving protocatechuate 4,5-dioxygenase

Overexpression of P-selectin glycoprotein ligand-1 enhances adhesive properties of endothelial progenitor cells through Syk activation

Regulation of membrane band 3 Tyr-phosphorylation by proteolysis of p72Syk and possible involvement in senescence process

Syk is low-expressed in non-small-cell lung cancer and inversely correlates with patient's survival

Tyrosine Phosphorylation and Syk Activation Are Involved in Thrombin-Induced Aggregation of Epinephrine-Potentiated Platelets

The Syk Inhibitor Fostamatinib Decreases the Severity of Colonic Mucosal Damage in a Rodent Model of Colitis

p72syk protein tyrosine kinase: an early transducer of sIgG-triggered apoptotic signalling in human follicular lymphoma cells.

Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis

Distinctive Functions of Syk N-Terminal and C-Terminal SH2 Domains in the Signaling Cascade Elicited by Oxidative Stress in B Cells

SP168MINCLE MAINTAINS M1 MACROPHAGE ACTIVATION VIA TLR4/NF-κB/SYK TO PROMOTE RENAL INFLAMMATION

 

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A nonreceptor tyrosine kinase (spleen tyrosine kinase, 630 aa) more widely expressed in myeloid and lymphoid cells than zap70 and involved in coupling activated immunoreceptors to downstream signalling events controlling proliferation, differentiation, and phagocytosis. It has two tandem SH2 domains that bind phosphorylated ITAM motifs.

Subjects: Chemistry — Medicine and Health.


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