Overview

synapsins


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RAB

 

'synapsins' can also refer to...

synapsins

synapsin I

Synapsin- and Actin-Dependent Frequency Enhancement in Mouse Hippocampal Mossy Fiber Synapses

Epileptic Synapsin Triple Knockout Mice Exhibit Progressive Long-Term Aberrant Plasticity in the Entorhinal Cortex

H3K4 tri-methylation in synapsin genes leads to different expression patterns in bipolar disorder and major depression

Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II−/− Mouse

Synaptic and Extrasynaptic Origin of the Excitation/Inhibition Imbalance in the Hippocampus of Synapsin I/II/III Knockout Mice

Opposite Changes in Glutamatergic and GABAergic Transmission Underlie the Diffuse Hyperexcitability of Synapsin I–Deficient Cortical Networks

PM450. Effects of olanzapine, clozapine, risperidone and sertindole on FGF2, synapsin and NGF expression in the hippocampus of naive mice

A Single Brain-Derived Neurotrophic Factor Infusion into the Dorsomedial Prefrontal Cortex Attenuates Cocaine Self-Administration-Induced Phosphorylation of Synapsin in the Nucleus Accumbens during Early Withdrawal

PM431. Effects of iloperidon and nemonaprid on depression, anxiety-like behaviour and locomotion: Altered gen expression levels of FGF2, synapsin and NGF in the hippocampus of mice

PM434. Haloperidol exerts depression-like behaviour in the forced swimming test while it has anxiolytic-like and analgesic effects in the elevated plus maze and hot plate tests: Altered gen expression levels of FGF2, synapsin and NGF in the hippocampus of mice.

 

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A family of phosphoproteins associated with synaptic vesicles and that interact with small G proteins such as rab to regulate neurotransmitter release and are phosphorylated by various kinases. They are also implicated in axonogenesis and synaptogenesis. Synapsin Ia (Brain protein 4.1, 705 aa) and Ib are alternatively spliced variants, as are synapsins IIa and IIb (582 aa). A third synapsin ( synapsin III, 580 aa) has a more restricted distribution. Mutations in synapsin I may be associated with X-linked disorders with primary neuronal degeneration such as Rett's syndrome.

Subjects: Medicine and Health — Chemistry.


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