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synthetic lethal


'synthetic lethal' can also refer to...

synthetic lethal

synthetic lethal

Synthetic Lethality: Killing Cancer With Cancer

Running Interference: Pace Picks Up on Synthetic Lethality Research

DN-01BYPASSING GLIOBLASTOMA RESISTANCE TO EGFR INHIBITORS BY SYNTHETIC LETHALITY

Gene function prediction from synthetic lethality networks via ranking on demand

BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability

Genetic synthetic lethality screen at the single gene level in cultured human cells

Fast-SL: an efficient algorithm to identify synthetic lethal sets in metabolic networks

HG-78SYNTHETIC LETHAL EPIGENETIC INTERACTIONS IN K27M MUTATED DIPG

SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets

Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint

P01.19A GENOME-WIDE RNAI SYNTHETIC LETHAL SCREEN FOR SENSITIZERS OF GLIOBLASTOMA MULTIFORME TO TEMOZOLOMIDE

Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM

Enhanced non-homologous end joining contributes toward synthetic lethality of pathological RAD51C mutants with poly (ADP-ribose) polymerase

Genome-wide mapping of unexplored essential regions in the Saccharomyces cerevisiae genome: evidence for hidden synthetic lethal combinations in a genetic interaction network

Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction

Mutations in the histone fold domain of the TAF12 gene show synthetic lethality with the TAF1 gene lacking the TAF N‐terminal domain (TAND) by different mechanisms from those in the SPT15 gene encoding the TATA box‐binding protein (TBP)

 

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A lethal chromosome derived from normally viable chromosomes by crossing over.

Subjects: Genetics and Genomics.


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