Overview

systemic sclerosis


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A rare connective-tissue disease affecting many systems in the body, mainly in women (3–6:1) in their forties. Genetic and autoimmune factors are implicated. In the diffuse form of the disease, besides scleroderma, there may be involvement of the lungs, with pulmonary fibrosis; renal failure and gastrointestinal and myocardial disease also occur. The limited form is also called CREST syndrome.

Subjects: Medicine and Health.


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