'TFII' can also refer to...




COUP-TFII Expressing Interneurons in Human Fetal Forebrain

TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress

Molecular and Electrophysiological Characterization of GABAergic Interneurons Expressing the Transcription Factor COUP-TFII in the Adult Human Temporal Cortex

A sequence motif conserved in diverse nuclear proteins identifies a protein interaction domain utilised for nuclear targeting by human TFIIS

Genomic and proteomic analysis of transcription factor TFII-I reveals insight into the response to cellular stress

Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells

RNA polymerase II complexes in the very early phase of transcription are not susceptible to TFIIS-induced exonucleolytic cleavage

Genes Encoding Isoforms of Transcription Elongation Factor TFIIS in Xenopus and the Use of Multiple Unusual RNA Processing Signals

The Transcription Factors COUP-TFI and COUP-TFII have Distinct Roles in Arealisation and GABAergic Interneuron Specification in the Early Human Fetal Telencephalon

Multiple domains for initiator binding proteins TFII-I and YY-1 are present in the initiator and upstream regions of the rat XDH/XO TATA-less promoter

A Duplicated Gene in the Breakpoint Regions of the 7q11.23 Williams-Beuren Syndrome Deletion Encodes the Initiator Binding Protein TFII-I and BAP-135, a Phosphorylation Target of BTK


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General transcription factors (TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIG/TFIIJ, and TFIIH) involved in the activity of RNA polymerase II and formation of the RNA polymerase II preinitiation complex. TFIID is a multicomponent transcription factor that recognizes and binds to the TATA-box promoter with the TATA-binding protein (TBP) subunit and has several TBP-associated factors (or TAFs). TFIID nucleates the transcription complex, recruiting the rest of the factors through a direct interaction with TFIIB. TFIIA interacts with the TBP subunit of TFIID and aids in the binding of TBP. TFIIB forms a complex with TFIID and TFIIA and bridges between IID and the polymerase. Mutations in TFIIB cause a shift in the transcription start site. TFIIE regulates initiation of transcription, TFIIF helps recruit polymerase II to the initiation complex in collaboration with TFIIB. TFIIH consists of ten subunits: some have helicase and ATPase activities, some phosphorylate serine residues in the polymerase, others are associated with cell cycle control. TFIIH is also involved in nucleotide excision repair. Other components ( TFIIG, TFIIJ ) also associate with the complex. TFIIX is a general name for various TBP accessory proteins.

Subjects: Medicine and Health.

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