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Bacterial exotoxins (oxygen-labile haemolysins) that bind to cholesterol in cell membranes and cause cytolysis by forming ring-like pores. The SH-groups of these toxins must be in the reduced state for activity and oxidation renders them inactive. Examples include tetanolysin, streptolysin O, θ-toxin (perfringolysin), cereolysin.
Subjects: Medicine and Health.
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