thrombotic thrombocytopenic purpura

Quick Reference

(TTP) a rare disorder of coagulation caused by deficiency or inhibition of ADAMTS13, a protein that is responsible for breaking down von Willebrand factor (see von Willebrand’s disease). This results in haemolytic anaemia, thrombocytopenia, and fluctuating neurological abnormalities. It is treated by plasmapheresis.

Subjects: Medicine and Health.

Reference entries