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A method of analysis used mainly in chemistry and immunology. In chemistry, it consists of slowly mixing a reagent into a solution until an identifiable end point, such as a color change, occurs. The concentration or quantity of the reagent at this end point is the basis for calculating quantitative and/or qualitative characteristics of the solution under investigation. In immunology, similar methods are used to calculate antibody titer in serum.

Subjects: Public Health and Epidemiology.

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