topoisomerase poisons

Show Summary Details

Quick Reference

Compounds such as Adriamycin (q.v.) that inhibit DNA polymerase II and cause cells to arrest at the DNA damage checkpoint (q.v.). Poisoned cells subsequently undergo apoptosis (q.v.).

Subjects: Genetics and Genomics.

Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.