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tram


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1. TRAM1 (thyroid hormone receptor activator molecule 1) is a nuclear receptor coactivator (NCOA3, steroid receptor coactivator-3) that binds nuclear receptors in a hormone-dependent fashion. NCOA3 recruits two other nuclear factors, CBP (CREB binding protein) and PCAF (p300/CBP-associated factor), into a multisubunit complex that stimulates transcription.

2. See translocating chain-associating membrane protein.

3. TRIF-related adaptor molecule (TRAM), see TIR domain.

Subjects: Medicine and Health.


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