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A myeloma cell into which immunoglobulin genes, either wild type or altered in vitro, have been transfected and expressed. Novel chimeric immunoglobulin molecules can be produced by this technique, including unique combinations of heavy and light chains, or combinations of variable regions with different constant regions (both within and between species). Contrast with hybridoma. See immunoglobulin.

Subjects: Genetics and Genomics.

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