translocation Down syndrome

'translocation Down syndrome' can also refer to...


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Familial Down syndrome, caused by having three copies of chromosome 21—two as separate chromosomes and one translocated to another chromosome, usually number 14. In families where one parent is a translocation heterozygote, the probability of having a child with Down syndrome is ˙33. See Chronology, 1960, Polani et al.

Subjects: Genetics and Genomics.

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