7 transmembrane domain (7TM) receptor

'7 transmembrane domain (7TM) receptor' can also refer to...


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An integral protein (q.v.) belonging to a large superfamily of transmembrane receptors that contain seven membrane-spanning domains. Most of the members of 7 TM receptors are G protein-coupled receptors (q.v.), each of which binds a signaling molecule on the extracellular side of the membrane and transduces a signal on the cytoplasmic side to initiate or inhibit biochemical reactions within the cell. Examples of 7 TM receptors are sensory and neurotransmitter receptors.

Subjects: Genetics and Genomics.

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