An enzyme that catalyses the formation of an amide linkage between a free amino group and a carbonyl group. The crosslinking of peptidoglycan in bacterial cell walls, carried out by a transpeptidase (EC 188.8.131.52), is blocked by penicillin-type antibiotics. Peptidyl transferase is an aminoacyltransferase (EC 184.108.40.206), a function that is also carried out by ribosomes. d-Glutamyl transpeptidase (d-glutamyltransferase, EC 220.127.116.11) forms a link between d-glutamine and d-glutamyl-peptide.
Subjects: Medicine and Health — Chemistry.