triggering receptor expressed on myeloid cells 2

Show Summary Details

Quick Reference


One of a family of receptors that regulate myeloid cell function. TREM-2 is expressed on macrophages, microglia, and pre-osteoclasts and signals through the adaptor DAP12. Defects of TREM-2 and DAP12 result in a rare syndrome characterized by presenile dementia and bone cysts.

Subjects: Medicine and Health.

Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.