TSPY gene

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A Y-linked gene which is the most spectacular example of a tandemly amplified gene in mammals. It encodes a testis-specific protein that is concentrated in the cytoplasm of spermatogonia (q.v.). Humans contain 20–60 copies of this gene, bulls up to 200. See human Y chromosome, Y chromosome, Y linkage.

Subjects: Genetics and Genomics.

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