tumour necrosis factor

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(TNF) either of two proteins, TNF-α or TNF-β, that function as cytokines. Produced by macrophages, monocytes, T lymphocytes, and various other cells, they mediate many responses, including inflammation, and have a marked action against tumour cells. Anti-TNF drugs (see cytokine inhibitor) are used in the treatment of several disorders, especially rheumatoid arthritis.

Subjects: Biological Sciences — Medicine and Health.

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