Overview

UBE3A


'UBE3A' can also refer to...

UBE3A

UBE3A and the Angelman Syndrome

Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a

Maternal disruption of Ube3a leads to increased expression of Ube3a-ATS in trans

Ube3a expression is not altered in Mecp2 mutant mice

Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase

Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3

The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor

Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome

Imprinted expression of UBE3A in non-neuronal cells from a Prader–Willi syndrome patient with an atypical deletion

The IC-SNURF–SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A

Deficiency of Ube3a in Huntington's disease mice brain increases aggregate load and accelerates disease pathology

Analysis of cerebellar function in Ube3a-deficient mice reveals novel genotype-specific behaviors

MeCP2 deficiency in Rett syndrome causes epigenetic aberrations at the PWS/AS imprinting center that affects UBE3A expression

Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin–proteasome pathway processes

Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a

Highly parallel SNP genotyping reveals high-resolution landscape of mono-allelic Ube3a expression associated with locus-wide antisense transcription

Regulation of the large (∼1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn

Ube3a deficiency inhibits amyloid plaque formation in APPswe/PS1δE9 mouse model of Alzheimer’s disease

 

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symbol for a gene encoding ubiquitin protein ligase E3A, which functions by attaching the small protein ubiquitin to proteins targeted for degradation within proteasomes. Mutations in the gene are responsible ...

Subjects: Chemistry.


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