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urocortin


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urocortin

urocortin

Urocortin induces positive inotropic effect in rat heart

Urocortin 2 infusion in human heart failure

154 Urocortin 2 acutely decreases myocardial stiffness

Urocortin-induced relaxation in the human internal mammary artery

Exploring new drugs for heart failure: the case of urocortin

Urocortin 3: haemodynamic, hormonal, and renal effects in experimental heart failure

Mechanism of urocortin expression and cardioprotection in ischaemic cardiac myocytes

Increased Alcohol Consumption in Urocortin 3 Knockout Mice Is Unaffected by Chronic Inflammatory Pain

Relaxation by urocortin of rat renal arteries: effects of diabetes in males and females

Mechanisms underlying the activation of L-type calcium channels by urocortin in rat ventricular myocytes

Suppression of progesterone production by stresscopin/urocortin 3 in cultured human granulosa-lutein cells

Secretory endometrium highly expresses urocortin messenger RNA and peptide: possible role in the decidualization process

Endogenous urocortins reduce vascular tone and renin–aldosterone/endothelin activity in experimental heart failure

The Modulation of Cardiac Contractile Function by the Pharmacological and Toxicological Effects of Urocortin2

478 The urocortin 2-induced decrease in myocardial stiffness is compromised in heart failure

479 Increased inotropic and lusitropic responses to urocortin 2 in the presence of endocardial endothelial dysfunction

670 Urocortin 1 exhibits potent inhibition of cardiac sympathetic nerve activity in ambulant sheep

 

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A small family of neuropeptides of the CRF (corticotropin-releasing factor) family synthesized in the anterior pituitary. Urocortin I (40 aa; 123 aa precursor) stimulates secretion of ACTH through the type 1 corticotropin-releasing hormone receptor (CRH receptor) that mediates the ‘fight or flight’ response. Urocortin II (urocortin-related peptide, stresscopin-related peptide, 43 aa) and urocortin III (stresscopin, 40 aa) are specific ligands for the type-2 CRH receptor which mediates stress-coping responses.

Subjects: Medicine and Health.


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