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The Latin scientific name for smallpox. Two varieties of smallpox were clinically defined. Variola major was a dangerous disease with very severe symptoms, extensive rash that could be hemorrhagic, and a case fatality ratio of 30% to 40%. Variola minor, alastrim, was less severe clinically, had a less extensive and nonhemorrhagic rash, and had a case fatality rate of 5% or less. The World Health Assembly of 1980 declared smallpox eradicated from the world.

Subjects: Public Health and Epidemiology.

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