Overview

vesicular monoamine transporters


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Members of the solute carrier 18 family (SLC18A1 and -2) that transport cytosolic monoamines (dopamine, serotonin) into synaptic vesicles. They are an important element of the monoaminergic neurotransmission systems, which are implicated in various neuropsychiatric disorders. They are inhibited by reserpine and tetrabenazine.

Subjects: Medicine and Health.


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