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villin


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A calcium-regulated, actin-binding protein (827 aa), a major structural component of the microfilament bundles of microvilli in the brush border. It severs microfilaments at high calcium concentrations, caps them at lower levels. Villin 2 (cytovillin, ezrin) is expressed strongly in placental syncytiotrophoblasts and in certain human tumours.

Subjects: Chemistry — Medicine and Health.


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