vinca alkaloid

Show Summary Details

Quick Reference

One of a group of antimitotic drugs (see also cytotoxic drug) derived from the periwinkle (Vinca rosea). Vinca alkaloids are used especially to treat leukaemias and lymphomas; they include vinblastine (Velbe), vincristine (Oncovin), and vindesine (Eldisine), which are administered intravenously. Vinorelbine (Navelbine), which can be administered intravenously or orally, is used in the treatment of advanced breast cancer and non-small-cell lung cancer. Vinca alkaloids are highly toxic; side-effects include myelosuppression, peripheral neuropathy, and severe irritation at the injection site.

Subjects: Medicine and Health.

Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.