Overview

Wolman disease


'Wolman disease' can also refer to...

 

More Like This

Show all results sharing these subjects:

  • Genetics and Genomics
  • Chemistry

GO

Show Summary Details

Quick Reference

A lysosomal storage disease frist described by M. Wolman and three colleagues in 1961. The condition is inherited as an autosomal recessive, and it is due to a deficiency of an acid lipase which leads to progressive accumulation of triglycerides and cholesterol esters in lysosomes of homozygotes. The mutations responsible are in a gene symbolized LIPA (for lipase A), and it is located between bands 24 and 25 on the long arm of chromosome 10.

Subjects: Genetics and Genomics — Chemistry.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.