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xeroderma


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n. a mild form of the hereditary disorder ichthyosis, in which the skin develops slight dryness and forms branlike scales. It is common in the elderly. Xeroderma pigmentosum is a rare genetically determined disorder (see genodermatosis) in which there is an inherited defect in the DNA repair mechanism in the skin, which corrects ultraviolet radiation damage; this leads to multiple skin cancers. Affected individuals must avoid exposure to sunlight.

Subjects: Medicine and Health.


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