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yaba virus


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A double-stranded DNA virus (yaba monkey tumour virus) that induces the formation of focal (benign) histiocytomas. It was isolated from African monkeys but can infect all primates. The genome encodes a TNFα binding protein (YMTV-2L, 341 aa) and inhibits TNF signalling. The yatapoxvirus genus has three members: tanapox virus (TPV), yaba-like disease virus (YLDV), and yaba monkey tumour virus.

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