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Z-DEVD


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A tetrapeptide (DEVD; l-aspartyl-l-glutamyl-l-valyl-l-aspartic acid amide) with a benzyloxycarbonyl (Z- or BOC-group) at the N-terminus that is a substrate for caspase 3. Often conjugated with rhodamine or other fluorochromes for chromogenic assays or fluoromethyl ketone (FMK)-derivatized to act as an irreversible caspase inhibitor.

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