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ZJ-43


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An inhibitor of peptidases that break down the neurotransmitter N-acetylaspartylglutamate (NAAG) which suppresses glutamate transmission through selective activation of the presynaptic group II metabotropic glutamate receptor subtype 3 (mGluR3). It may potentially reduce neuronal and astrocyte damage associated with glutamate excitotoxicity after brain injury.

Subjects: Medicine and Health.


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