Overview

apelin


'apelin' can also refer to...

apelin

On the cardiovascular activity of apelin

Apelin and vascular dysfunction in type 2 diabetes

Reduced apelin levels in lone atrial fibrillation

Cardiac resynchronization therapy increases plasma levels of the endogenous inotrope apelin

The role of apelin in cardiovascular function and heart failure

Unanticipated role of apelin: regulation of miRNA generation

Plasma apelin concentration is depressed following acute myocardial infarction in man

Biology of the apelin-APJ axis in vascular formation

Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway

472 EAdministration of Apelin modulates myocardial expression of Apelin-APJ and improves right ventricular performance in MCT-induced pulmonary hypertension

Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure

Hypoxia promotes bone marrow-derived mesenchymal stem cell proliferation through apelin/APJ/autophagy pathway

Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice

The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo

ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13

Apelin and APJ, a novel critical factor and therapeutic target for atherosclerosis

Neu-p11 reduces clock/apelin expression in insulin-resistant mouse adipocyte model

304Nuclear targeting apelin induces phenotypic transition of vascular smooth muscle cells

 

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Quick Reference

The endogenous ligand for the G-protein-coupled receptor APJ. The peptide (77 aa) is cleaved into various active fragments (apelins-13, -28, -31, and -36). It will inhibit HIV-1 entry in cells coexpressing CD4 and APJ. It is expressed in the brain and secreted by the mammary gland into colostrum and milk.

Subjects: Medicine and Health.


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