base analogue

'base analogue' can also refer to...

base analogue

base analogue

base analogue

base analogue

base analogue

Insulin glargine: a new basal insulin analogue

Characterization and Use of Tricyclic Fluorescent Nucleic Acid Base Analogues

HPLC Separation of Tetracycline Analogues: Comparison Study of Laser-Based Polarimetric Detection with UV Detection

Structure-based design of a streptavidin mutant specific for an artificial biotin analogue

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA

Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue

Synthesis of 5′-branched neplanocin A analogues based on radical-mediated sulfur-extrusive stannylation

Challenges for forecasting based on accelerating rates of earthquakes at volcanoes and laboratory analogues

Are Nonnucleoside Analogue–Based Regimens Better than Protease Inhibitor–Based Regimens for Nonadherent HIV-Infected Patients?

Pre-clinical safety evaluation of novel nucleoside analogue-based dual-function microbicides (WHI-05 and WHI-07)

Simultaneous evaluation of basal FSH and oestradiol response to GnRH analogue (F-G-test) allows effective drug regimen selection for IVF

DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization

3CAPS – a structural AP–site analogue as a tool to investigate DNA base excision repair

Electronic transition moments of 6-methyl isoxanthopterin—a fluorescent analogue of the nucleic acid base guanine


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A purine or pyrimidine base (see base pair) that differs slightly in structure from the normal base, but that because of its similarity to that base may act as a mutagen when incorporated into DNA. Once in place, these bases, which have pairing properties unlike those of the bases they replace, can produce mutations by causing insertions of incorrect nucleotides opposite them during replication. Though the original base analogue exists only in a single strand, it can cause a nucleotide-pair substitution that is replicated in all DNA copies descended from that original strand. An example is 5-bromo-uracil (5BU), an analogue of thymine that has bromine at the C-5 position in place of the CH3 group found in thymine.

Subjects: Plant Sciences and Forestry.

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