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base analogue


'base analogue' can also refer to...

base analogue

base analogue

base analogue

base analogue

base analogue

Insulin glargine: a new basal insulin analogue

Characterization and Use of Tricyclic Fluorescent Nucleic Acid Base Analogues

Challenges for forecasting based on accelerating rates of earthquakes at volcanoes and laboratory analogues

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA

Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue

Synthesis of 5′-branched neplanocin A analogues based on radical-mediated sulfur-extrusive stannylation

Structure-based design of a streptavidin mutant specific for an artificial biotin analogue

HPLC Separation of Tetracycline Analogues: Comparison Study of Laser-Based Polarimetric Detection with UV Detection

Are Nonnucleoside Analogue–Based Regimens Better than Protease Inhibitor–Based Regimens for Nonadherent HIV-Infected Patients?

Electronic transition moments of 6-methyl isoxanthopterin—a fluorescent analogue of the nucleic acid base guanine

Solution structure and dynamics of DNA duplexes containing the universal base analogues 5-nitroindole and 5-nitroindole 3-carboxamide

Fluorescent properties of DNA base analogue tC upon incorporation into DNA — negligible influence of neighbouring bases on fluorescence quantum yield

Ambiguous Base Pairing of the Purine Analogue 1-(2-Deoxy-β-d-Ribofuranosyl)-Imidazole-4-Carboxamide during PCR

Triplex formation involving 2′,4′-BNA with 2-pyridone base analogue: Efficient and selective recognition of C:G interruption

 

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Quick Reference

A purine or pyrimidine base (see base pair) that differs slightly in structure from the normal base, but that because of its similarity to that base may act as a mutagen when incorporated into DNA. Once in place, these bases, which have pairing properties unlike those of the bases they replace, can produce mutations by causing insertions of incorrect nucleotides opposite them during replication. Though the original base analogue exists only in a single strand, it can cause a nucleotide-pair substitution that is replicated in all DNA copies descended from that original strand. An example is 5-bromo-uracil (5BU), an analogue of thymine that has bromine at the C-5 position in place of the CH3 group found in thymine.

Subjects: Plant Sciences and Forestry.


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