CCN family

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A family of proteins involved in cell differentiation and function, that interact with integrins and modulate their activity. The family includes cysteine-rich 61 (CYR61/CCN1, cysteine-rich angiogenic inducer 61, 381 aa), connective tissue growth factor (CTGF/CCN2), nephroblastoma overexpressed (nov/CCN3), and Wnt-induced secreted proteins (WISP) 1, 2, and 3. (CCN4, CCN5, and CCN6).

Subjects: Medicine and Health.

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