chromosomal passenger complex

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A multiprotein complex consisting of aurora B kinase, inner centromere protein (INCENP), borealin, and survivin that acts as a key regulator of mitosis. It has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.

http://www.celldiv.com/content/3/1/10 An article from the journal Cell Division (2008) gives more details.

Subjects: Medicine and Health.

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