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Coombs' test


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A means of detecting rhesus antibodies on the surface of red blood cells that precipitate proteins (globulins) in the blood serum. The test is used in the diagnosis of haemolytic anaemia in babies with rhesus incompatibility in whom there is destruction of red blood cells (see haemolytic disease of the newborn). R. R. A. Coombs (1921–2006), British immunologist

Subjects: Medicine and Health.


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