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farnesyltransferase


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farnesyltransferase

Activity of SCH 66336, a tricyclic farnesyltransferase inhibitor, against human tumor colony-forming units

Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336

Phase II trial of the farnesyltransferase inhibitor tipifarnib plus fulvestrant in hormone receptor-positive metastatic breast cancer: New York Cancer Consortium Trial P6205

Hypoxia-inducible Factor 1α and Antiangiogenic Activity of Farnesyltransferase Inhibitor SCH66336 in Human Aerodigestive Tract Cancer

High-level expression, purification, kinetic characterization and crystallization of protein farnesyltransferase β-subunit C-terminal mutants

Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Incomplete processing of mutant lamin A in Hutchinson–Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition

A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency

Shoot-Specific Down-Regulation of Protein Farnesyltransferase (α-Subunit) for Yield Protection against Drought in Canola

Induction of micronuclei by a new non-peptidic mimetic farnesyltransferase inhibitor RPR-115135: role of gene mutations

Effects of Insulin-like Growth Factor Binding Protein-3 and Farnesyltransferase Inhibitor SCH66336 on Akt Expression and Apoptosis in Non–Small-Cell Lung Cancer Cells

Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas

 

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EC 2.5.1.21; recommended name: farnesyl‐diphosphate farnesyltransferase; systematic name: farnesyl‐diphosphate:farnesyl‐diphosphate farnesyltransferase; other name: presqualene‐diphosphate synthase. An enzyme that catalyses the formation of presqualene diphosphate from two molecules of farnesyl diphosphate with ...

Subjects: Chemistry.


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