Overview

interleukin-27


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(IL-27)

A heterodimeric member of the IL-6/IL-12 family cytokines, with one subunit related to the p40 subunit of IL-12 and IL-23 and the other (p28; IL-30) related to the p35 chain of IL-12. Has both anti- and proinflammatory properties and is expressed by monocytes, endothelial cells, and dendritic cells.

Subjects: Medicine and Health.


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