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kappa toxin


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1. An exotoxin produced by Clostridium perfringens; a collagenase responsible for the tissue damage in gas gangrene.

2. κ-Hefutoxin-1 and -2, isolated from the venom of the scorpion Heterometrus fulvipes, block the voltage-gated potassium channels Kv1.3 and Kv1.2 and slow the activation kinetics of Kv1.3 currents; they have no homology to any other toxins.

Subjects: Medicine and Health.


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