n. an antiretroviral (ARV) drug used, in combination with other ARVs, for treating refractory HIV infection. It acts by binding to and antagonizing CCR5, a receptor for a class of chemokines on the host cell needed by some HIV viruses to enter the cell. It is administered orally; side-effects include gastrointestinal upsets, cough, and dizziness. Trade name: Celsentri.
Subjects: Clinical Pharmacology and Therapeutics.