Overview

natalizumab


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n. a monoclonal antibody used for the treatment of severe relapsing-remitting multiple sclerosis: it reduces demyelination and inflammation by inhibiting migration of leucocytes into the central nervous system. It is administered by intravenous infusion; side-effects include an increased risk of neurological damage and opportunistic infections. Trade name: Tysabri.

Subjects: Clinical Pharmacology and Therapeutics.


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