Related Overviews


More Like This

Show all results sharing these subjects:

  • Medicine and Health
  • Chemistry


Quick Reference

A family of serum proteins (EC, 40–45-kDa glycoproteins) that associate with high density lipoprotein (HDL) and are important in detoxification of organophosphates, aromatic esters, nerve agents such as sarin, and various other organic compounds. The isoforms have different substrate specificities. There are multiple polymorphisms in the PON1 and PON2 genes, some associated with altered risk of coronary artery disease and sensitivity to organophosphates.

Subjects: Medicine and Health — Chemistry.

Reference entries