A family of proteins that can form pentameric (or decameric) complexes, have the ability to bind numerous ligands and may be involved in nonspecific uptake of bacteria and cell debris. Pentraxin 1 is expressed mostly in brain and binds snake venom toxin taipoxin. Pentraxin 2 is more widely distributed. Pentraxin 3 (pentaxin 3) binds various pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa, and Salmonella typhimurium. Other members of the family are C-reactive protein and serum amyloid P.
Subjects: Medicine and Health.