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Frogs of this genus have been used widely in research. The leopard frog, R. pipiens, is the most common species bred in the laboratory, and many of its mutations have been recovered and analyzed. This was the species in which the first experiments were performed involving transfer of somatic diploid nuclei into enucleated eggs. Mutant strains are also available for R. sylvatica, R. esculenta, and R. temporaria. R. esculenta is the only anuran for which working maps of the lamp-brush chromosomes are available. See Chronology, 1952, Briggs and King.

Subjects: Genetics and Genomics.

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