RNase protection

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A technique for locating the points of effective contact between a nucleic acid chain and a cognate polypeptide chain; the complex (e.g., tRNA and its cognate aminoacyl-tRNA synthetase) is treated with a group of RNases that digest all of the RNA except those regions in contact with the synthetase. See photoactivated cross-linking.

Subjects: Genetics and Genomics.

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