signal peptide

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A sequence of about 20 amino acids at or near the amino terminus of a polypeptide chain that attaches the nascent polypeptide and its ribosome to the endoplasmic reticulum. Polypeptides thus anchored are “flagged” to be processed in the Golgi apparatus prior to release from the cell. See Chronology, 1999, Blobel.

Subjects: Chemistry.

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