The most studied gene, which controls the biological clock of Neurospora. Mutations of frq either shorten or lengthen the period between conidiations. The frq gene has been cloned, and it gives rise to at least two processed transcripts. The longer transcript arises from an ORF of 2,364 base pairs. Although the predicted protein product of frq has an amino acid sequence that shows no extended similarities to any previously described protein, there is a segment about 50 amino acids long with sequence similarities to the per gene of Drosophila. See period.
Subjects: Genetics and Genomics.