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1. The product of a gene mutated in a murine model of Hermansky–Pudlak syndrome that is involved in the development of lysosome-related organelles, such as melanosomes and platelet-dense granules. The human homologue (217 aa) interacts with pallidin and muted proteins in the BLOC-1 complex.

2. An actin-nucleation factor that regulates the onset of ooplasmic streaming in Drosophila, a maternal-effect locus important for pattern formation in the early embryo. There are multiple isoforms ranging from 819 aa to 1361 aa.

Subjects: Medicine and Health.

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