Extreme mental or physical suffering.
agony column originally (in the mid 19th century) the column of a newspaper containing special advertisements, particularly those for missing relatives or friends, and thus containing evidence of great distress. Later (the current meaning), it became a column in a newspaper or magazine offering advice on personal problems to readers who write in. An agony aunt is the female author of a newspaper column providing such advice.
Agony in the Garden the anguish of Christ in the Garden of Gethsemane, as in Luke 22:44; agony in this passage is used in Wyclif's translation.